Gradient
Denervation Technologies

A device based solution to treat heart failure with associated pulmonary hypertension

Our Vision

The therapeutic approach developed by Gradient Denervation Technologies aims improving cardiovascular health.

Management team

CEO - Martin Grasse
CFO - Greg Mann
CTO - David Amaoua
COO - Julie Messer

Board of Directors

Director - Evan Castiglia

Director - Lisa Wipperman Heine

CEO/Director - Martin Grasse

Observer/Founder - Dr Swami Gnanashanmugam

Director - Juan Pablo Mas

Director - Mano Iyer

Director - Sylvain Sachot, PhD

Press Releases

Gradient Denervation Technologies Enrolls First Patient in Early Feasibility Study of Pulmonary Artery Denervation System

PARIS, FRANCE, March 6, 2024 — FDA-Approved US study intended to evaluate pulmonary artery denervation in heart failure patients with WHO Group 2 Pulmonary Hypertension Read more
Gradient Denervation Technologies closes €14m Series A led by Sabadell Asabys

PARIS, FRANCE, SEPTEMBER 7, 2023
  • Thuja Capital and founding investor Sofinnova Partners also joined the round
  • The funds will enable the company to advance the clinical development of its unique, minimally invasive ultrasound-based catheter for the treatment of pulmonary hypertension, with initial focus on the Group 2 population, or heart failure accompanied by high pulmonary vascular resistance Read more
  • Gradient Denervation Technologies enrolls initial patient in first-in-human study of pulmonary artery denervation technology

    PARIS, FRANCE, JUNE 1, 2023 — Gradient Denervation Technologies, a Paris-based medical device company developing a minimally-invasive device for treating certain heart failure patients with associated pulmonary hypertension, announced today the successful first patient enrollment in its first-in-human clinical study. Read more
    Gradient Denervation Technologies announces appointment of Martin Grasse as Chief Executive Officer

    PARIS, FRANCE, APRIL 7, 2022 - Gradient Denervation Technologies, a Paris-based medical device company developing a minimally-invasive solution for the treatment of heart failure patients with pulmonary hypertension, announced today the appointment of Martin Grasse as Chief Executive Officer. With over 15 years in the medical device industry, Grasse joins the company as it works to freeze the design of its novel catheter-based system and prepare for early clinical trials. Read more
    Gradient Denervation Technologies Raises €3.5M in Seed Funding with Sofinnova Partners

    PARIS, FRANCE, SEPTEMBER 17, 2020 - Gradient Denervation Technologies announced the close of a €3.5M seed financing from Sofinnova Partners to support the development of its intravascular, catheter-based technology. Read more

    Our Grants

    EIT Health Catapult

    2020 winner - Medtech 3rd place
    i-Lab 2020

    2020 Laureat

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